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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to RBPJ (N-term)

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别名:Recombining binding protein suppressor of hairless, CBF-1, J kappa-recombination signal-binding protein, RBP-J kappa, RBP-J, RBP-JK, Renal carcinoma antigen NY-REN-30, RBPJ, IGKJRB, IGKJRB1, RBPJK, RBPSUH
应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl

Description
Transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate. determinations. Acts as a transcriptional repressor when it is not associated with Notch proteins. When associated with some Notch protein, it acts as a transcriptional activator that activates transcription of Notch target genes. Probably represses or activates transcription via the recruitment of chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins, respectively. Specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence.
Specification
Aliases Recombining binding protein suppressor of hairless, CBF-1, J kappa-recombination signal-binding protein, RBP-J kappa, RBP-J, RBP-JK, Renal carcinoma antigen NY-REN-30, RBPJ, IGKJRB, IGKJRB1, RBPJK, RBPSUH
Entrez GeneID 3516
Swissprot Q06330
WB Predicted band size 55.6kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen This RBPJ antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-29 amino acids from the N-terminal region of human RBPJ.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

All lanes : Anti-RBPJ Antibody (N-term) at 1:1000 dilution
Lane 1: Hela whole cell lysate
Lane 2: CCRF-CEM whole cell lysate
Lane 3: MCF-7 whole cell lysate
Lane 4: Mouse testis lysate

Lysates/proteins at 20 µg per lane.

Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated (ASP1615) at 1/15000 dilution.

Observed band size : 56kDa

Blocking/Dilution buffer: 5% NFDM/TBST.


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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。