Rabbit Polyclonal Antibody to RCAN1

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:CSP1; DSC1; RCN1; DSCR1; MCIP1; ADAPT78
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.

Description

The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene.

Specification
Aliases	CSP1; DSC1; RCN1; DSCR1; MCIP1; ADAPT78
Swissprot	P53805
WB Predicted band size	28 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human RCAN1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/50-1/200
ELISA	1/2000-1/5000

	Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: Mouse heart tissue, Mouse brain tissue, Primary antibody: P11492(RCAN1 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P11492(RCAN1 Antibody) at dilution 1/45. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human brain tissue using P11492(RCAN1 Antibody) at dilution 1/45. (Original magnification: ×200)