Rabbit Polyclonal Antibody to RFX2

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别名:DNA-binding protein RFX2; Regulatory factor X 2;
应用:IHC
反应种属:Human
规格：50μl/100μl

Description
a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites.Reith W., Mol. Cell. Biol. 14:1230-1244(1994).Sjoeblom T., Science 314:268-274(2006).

Description

a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites.Reith W., Mol. Cell. Biol. 14:1230-1244(1994).Sjoeblom T., Science 314:268-274(2006).

Specification
Aliases	DNA-binding protein RFX2; Regulatory factor X 2;
Entrez GeneID	5990;
Swissprot	P48378
WB Predicted band size	80kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human RFX2.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.