中文 
别名:Regulator of G-protein signaling 19, RGS19, G-alpha-interacting protein, GAIP, RGS19, GAIP, GNAI3IP应用:WB,IHC
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| RGS19 enhances the intrinsic GTPase-activating protein activity of the Galphai3 protein, which stimulates autophagy by favoring the GDP-bound form of Galphai3.
Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). |
| Specification | |
|---|---|
| Aliases | Regulator of G-protein signaling 19, RGS19, G-alpha-interacting protein, GAIP, RGS19, GAIP, GNAI3IP |
| Entrez GeneID | 10287 |
| Swissprot | P49795 |
| WB Predicted band size | 24.6kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This RGS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9~39 amino acids surrounding S24 of human RGS19. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Application | |
|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
 |
All lanes : Anti-RGS19 Antibody (S24) at 1:1000 dilution Lane 1: human lung lysate Lane 2: human placenta lysate Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 25 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
 |
Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with RGS19 Antibody (S24) (Cat.#P34132), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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