Rabbit Polyclonal Antibody to RHG07

包装: 1G|100G|500G|1KG|100KG

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别名:Rho-type GTPase-activating protein 7; Deleted in liver cancer 1 protein; Dlc-1; HP protein; StAR-related lipid transfer protein 12
应用:IHC,ICC
反应种属:Human
规格：50μl/100μl

Description
Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.Yuan B.Z., Cancer Res. 58:2196-2199(1998).Nagase T., DNA Res. 7:347-355(2000).Wilson P.J., Hum. Mutat. 15:156-165(2000).

Description

Functions as a GTPase-activating protein for the small GTPases RHOA, RHOB, RHOC and CDC42, terminating their downstream signaling. This induces morphological changes and detachment through cytoskeletal reorganization, playing a critical role in biological processes such as cell migration and proliferation. Also functions in vivo as an activator of the phospholipase PLCD1. Active DLC1 increases cell migration velocity but reduces directionality.Yuan B.Z., Cancer Res. 58:2196-2199(1998).Nagase T., DNA Res. 7:347-355(2000).Wilson P.J., Hum. Mutat. 15:156-165(2000).

Specification
Aliases	Rho-type GTPase-activating protein 7; Deleted in liver cancer 1 protein; Dlc-1; HP protein; StAR-related lipid transfer protein 12
Entrez GeneID	10395;
Swissprot	Q96QB1
WB Predicted band size	123kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from internal of human RHG07.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
IHC	1/50-1/100
ICC	1/100-1/500

	Immunofluorescence analysis of A549 cells, using RHG07 antibody P42089.
	Immunohistochemistry analysis of paraffin-embedded human prostate carcinoma tissue, using RHG07 antibody P42089.