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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to RIPK3

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别名:Receptor-interacting serine/threonine-protein kinase 3, RIP-like protein kinase 3, Receptor-interacting protein 3, RIP-3, RIPK3, RIP3
应用:WB,IHC
反应种属:Human
规格:50μl/100μl

Description
The product of this gene is a member of the
receptor-interacting protein (RIP) family of serine/threonine
protein kinases, and contains a C-terminal domain unique from other
RIP family members. The encoded protein is predominantly localized
to the cytoplasm, and can undergo nucleocytoplasmic shuttling
dependent on novel nuclear localization and export signals. It is a
component of the tumor necrosis factor (TNF) receptor-I signaling
complex, and can induce apoptosis and weakly activate the NF-kappaB
transcription factor.
Specification
Aliases Receptor-interacting serine/threonine-protein kinase 3, RIP-like protein kinase 3, Receptor-interacting protein 3, RIP-3, RIPK3, RIP3
Entrez GeneID 11035
Swissprot Q9Y572
WB Predicted band size 56.9kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This RIPK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 480-509 amino acids from the C-terminal region of human RIPK3.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/500-1/1000
IHC 1/100-1/500

Anti-RIPK3 Antibody (C-term) at 1:500 dilution + HT-29 whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 57 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

RIPK3 Antibody (C-term) (Cat. #P33616) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RIPK3 antibody detected the RIPK3 protein (arrow).
RIPK3 Antibody (C-term) (P33616)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RIPK3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。