Rabbit Polyclonal Antibody to RIT1

包装: 1G|100G|500G|1KG|100KG

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别名:GTP-binding protein Rit1; Ras-like protein expressed in many tissues; Ras-like without CAAX protein 1; RIBB; RIT
应用:WB
反应种属:Human
规格：50μl/100μl

Description
Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.Manabu Furukawa, Mol. Cell. Biol., Nov 2000; 20: 8185 – 8197. Angus Chen, J. Biol. Chem., May 2000; 275: 15432. Kenneth Wu, Mol. Cell. Biol., Feb 2000; 20: 1382 – 1393. Kenneth Wu, J. Biol. Chem., Jan 2002; 277: 516 – 527.

Description

Plays a crucial role in coupling NGF stimulation to the activation of both EPHB2 and MAPK14 signaling pathways and in NGF-dependent neuronal differentiation. Involved in ELK1 transactivation through the Ras-MAPK signaling cascade that mediates a wide variety of cellular functions, including cell proliferation, survival, and differentiation.Manabu Furukawa, Mol. Cell. Biol., Nov 2000; 20: 8185 – 8197. Angus Chen, J. Biol. Chem., May 2000; 275: 15432. Kenneth Wu, Mol. Cell. Biol., Feb 2000; 20: 1382 – 1393. Kenneth Wu, J. Biol. Chem., Jan 2002; 277: 516 – 527.

Specification
Aliases	GTP-binding protein Rit1; Ras-like protein expressed in many tissues; Ras-like without CAAX protein 1; RIBB; RIT
Entrez GeneID	6016;
Swissprot	Q92963
WB Predicted band size	25kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from human RIT1.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000

	Western blot analysis of extracts from Jurkat cells, using RIT1 antibody P41833.
	Western blot analysis of extracts from K562 cells (Lane 2), JK cells (Lane 3) and 293 cells (Lane 4), using RIT1 antiobdy P41833. The lane on the left is treated with synthesized peptide.