Rabbit Polyclonal Antibody to RPGR

包装: 1G|100G|500G|1KG|100KG

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别名:X-linked retinitis pigmentosa GTPase regulator, RPGR, RP3, XLRP3
应用:WB
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a protein with a series of six RCC1-like domains (RLDs), characteristic of the highly conserved guanine nucleotide exchange factors. The encoded protein is found in the Golgi body and interacts with RPGRIP1. This protein localizes to the outer segment of rod photoreceptors and is essential for their viability. Mutations in this gene have been associated with X-linked retinitis pigmentosa (XLRP). Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length natures of only some have been determined.

Description

This gene encodes a protein with a series of six RCC1-like
domains (RLDs), characteristic of the highly conserved guanine
nucleotide exchange factors. The encoded protein is found in the
Golgi body and interacts with RPGRIP1. This protein localizes to
the outer segment of rod photoreceptors and is essential for their
viability. Mutations in this gene have been associated with
X-linked retinitis pigmentosa (XLRP). Multiple alternatively
spliced transcript variants that encode different isoforms of this
gene have been reported, but the full-length natures of only some
have been determined.

Specification
Aliases	X-linked retinitis pigmentosa GTPase regulator, RPGR, RP3, XLRP3
Entrez GeneID	6103
Swissprot	Q92834
WB Predicted band size	113.4kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This RPGR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 744-772 amino acids of human RPGR.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.