Rabbit Polyclonal Antibody to RPL22(C-term)

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:60S ribosomal protein L22, EBER-associated protein, EAP, Epstein-Barr virus small RNA-associated protein, Heparin-binding protein HBp15, RPL22
应用:WB
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 60S subunit. The protein belongs to the L22E family of ribosomal proteins. Its initiating methionine residue is post-translationally removed. The protein can bind specifically to Epstein-Barr virus-encoded RNAs (EBERs) 1 and 2. The mouse protein has been shown to be capable of binding to heparin. Transcript variants utilizing alternative polyA signals exist. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. It was previously thought that this gene mapped to 3q26 and that it was fused to the acute myeloid leukemia 1 (AML1) gene located at 21q22 in some therapy-related myelodysplastic syndrome patients with 3;21 translocations; however, these fusions actually involve a ribosomal protein L22 pseudogene located at 3q26, and this gene actually maps to 1p36.3-p36.2.

Description

Ribosomes, the organelles that catalyze protein synthesis,
consist of a small 40S subunit and a large 60S subunit. Together
these subunits are composed of 4 RNA species and approximately 80
structurally distinct proteins. This gene encodes a cytoplasmic
ribosomal protein that is a component of the 60S subunit. The
protein belongs to the L22E family of ribosomal proteins. Its
initiating methionine residue is post-translationally removed. The
protein can bind specifically to Epstein-Barr virus-encoded RNAs
(EBERs) 1 and 2. The mouse protein has been shown to be capable of
binding to heparin. Transcript variants utilizing alternative polyA
signals exist. As is typical for genes encoding ribosomal proteins,
there are multiple processed pseudogenes of this gene dispersed
through the genome. It was previously thought that this gene mapped
to 3q26 and that it was fused to the acute myeloid leukemia 1
(AML1) gene located at 21q22 in some therapy-related
myelodysplastic syndrome patients with 3;21 translocations;
however, these fusions actually involve a ribosomal protein L22
pseudogene located at 3q26, and this gene actually maps to
1p36.3-p36.2.

Specification
Aliases	60S ribosomal protein L22, EBER-associated protein, EAP, Epstein-Barr virus small RNA-associated protein, Heparin-binding protein HBp15, RPL22
Entrez GeneID	6146
Swissprot	P35268
WB Predicted band size	14.8kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	This RPL22 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-121 amino acids from the C-terminal region of human RPL22.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/2000

All lanes : Anti-RPL22 Antibody(C-term) at 1:2000 dilution
Lane 1: A431 whole cell lysate
Lane 2: HepG2 whole cell lysate
Lane 3: Neuro-2a whole cell lysate
Lane 4: human placenta lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 15 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。

暂无评论