Rabbit Polyclonal Antibody to RPS4Y1

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别名:40S ribosomal protein S4, Y isoform 1, RPS4Y1, RPS4Y
应用:WB,IHC,FCM
反应种属:Human
规格：50μl/100μl

Description
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, X-linked (RPS4X). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Description

Cytoplasmic ribosomes, organelles that catalyze protein
synthesis, consist of a small 40S subunit and a large 60S subunit.
Together these subunits are composed of 4 RNA species and
approximately 80 structurally distinct proteins. This gene encodes
ribosomal protein S4, a component of the 40S subunit. Ribosomal
protein S4 is the only ribosomal protein known to be encoded by
more than one gene, namely this gene and ribosomal protein S4,
X-linked (RPS4X). The 2 isoforms encoded by these genes are not
identical, but are functionally equivalent. Ribosomal protein S4
belongs to the S4E family of ribosomal proteins. It has been
suggested that haploinsufficiency of the ribosomal protein S4 genes
plays a role in Turner syndrome; however, this hypothesis is
controversial. As is typical for genes encoding ribosomal proteins,
there are multiple processed pseudogenes of this gene dispersed
through the genome.

Specification
Aliases	40S ribosomal protein S4, Y isoform 1, RPS4Y1, RPS4Y
Entrez GeneID	6192
Swissprot	P22090
WB Predicted band size	29.5kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This RPS4Y1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 76-105 amino acids from the Central region of human RPS4Y1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500
FCM	1/10-1/50

	RPS4Y1 Antibody (Center) (Cat. #P31164) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the RPS4Y1 antibody detected the RPS4Y1 protein (arrow).
	RPS4Y1 Antibody (Center) (Cat. #P31164) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
	RPS4Y1 Antibody (Center) (Cat. #P31164)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RPS4Y1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.