别名:KS6A1; KS6AA; MAPKAP-K1a; RSK1;应用:WB
反应种属:Human,Mouse
规格:50μl/100μl
Description |
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This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. Moller D.E., Am. J. Physiol. 266:C351-C359(1994)Gregory S.G., Nature 441:315-321(2006)The MGC Project Team, Genome Res. 14:2121-2127(2004). |
Specification | |
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Aliases | KS6A1; KS6AA; MAPKAP-K1a; RSK1; |
Entrez GeneID | 6195; |
Swissprot | Q15418 |
WB Predicted band size | 85kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human,Mouse |
Immunogen | Peptide sequence around phosphorylation site of Serine 221/227/218/232(A-Y-S(p)-F-C) derived from Human RSK1/2/3/4. |
Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
Application | |
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WB | 1/500-1/1000 |
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Western blot analysis of extracts from HepG2 cells (Lane 2), using RSK1/2/3/4 (Phospho-Ser221/227/218/232) Antibody P40454. The lane on the left is treated with antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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