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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to RSK1/2/3/4 (Phospho-Ser221/227/S218/232)

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别名:KS6A1; KS6AA; MAPKAP-K1a; RSK1;
应用:WB
反应种属:Human,Mouse
规格:50μl/100μl

Description
This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. Moller D.E., Am. J. Physiol. 266:C351-C359(1994)Gregory S.G., Nature 441:315-321(2006)The MGC Project Team, Genome Res. 14:2121-2127(2004).
Specification
Aliases KS6A1; KS6AA; MAPKAP-K1a; RSK1;
Entrez GeneID 6195;
Swissprot Q15418
WB Predicted band size 85kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Peptide sequence around phosphorylation site of Serine 221/227/218/232(A-Y-S(p)-F-C) derived from Human RSK1/2/3/4.
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
WB 1/500-1/1000

Western blot analysis of extracts from HepG2 cells (Lane 2), using RSK1/2/3/4 (Phospho-Ser221/227/218/232) Antibody P40454. The lane on the left is treated with antigen-specific peptide.

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。