中文 
别名:R-spondin-1, Roof plate-specific spondin-1, hRspo1, RSPO1应用:WB
反应种属:Human
规格：50μl/100μl
| Description |
|---|
| Activator of the canonical Wnt signaling pathway by acting as a ligand for LGR4-6 receptors. Upon binding to LGR4-6 (LGR4, LGR5 or LGR6), LGR4-6 associate with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. Also regulates the canonical Wnt/beta-catenin-dependent pathway and non-canonical Wnt signaling by acting as an inhibitor of ZNRF3, an important regulator of the Wnt signaling pathway. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway. Has a essential roles in ovary determination. |
| Specification | |
|---|---|
| Aliases | R-spondin-1, Roof plate-specific spondin-1, hRspo1, RSPO1 |
| Entrez GeneID | 284654 |
| Swissprot | Q2MKA7 |
| WB Predicted band size | 29.0kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human |
| Immunogen | This RSPO1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 206-240 amino acids from human RSPO1. |
| Application | |
|---|---|
| WB | 1/2000 |
 |
All lanes : Anti-RSPO1 Antibody (C-Term) at 1:2000 dilution Lane 1: HL-60 whole cell lysate Lane 2: Jurkat whole cell lysate Lane 3: K562 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 29 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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