Rabbit Polyclonal Antibody to SAR1B

包装: 1G|100G|500G|1KG|100KG

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别名:GTP-binding protein SAR1b, GTP-binding protein B, GTBPB, SAR1B, SARA2, SARB
应用:WB,IHC,FCM
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene is a small GTPase that acts as a homodimer. The encoded protein is activated by the guanine nucleotide exchange factor PREB and is involved in protein transport from the endoplasmic reticulum to the Golgi. This protein is part of the COPII coat complex. Defects in this gene are a cause of chylomicron retention disease (CMRD), also known as Anderson disease (ANDD). Two transcript variants encoding the same protein have been found for this gene.

Description

The protein encoded by this gene is a small GTPase that
acts as a homodimer. The encoded protein is activated by the
guanine nucleotide exchange factor PREB and is involved in protein
transport from the endoplasmic reticulum to the Golgi. This protein
is part of the COPII coat complex. Defects in this gene are a cause
of chylomicron retention disease (CMRD), also known as Anderson
disease (ANDD). Two transcript variants encoding the same protein
have been found for this gene.

Specification
Aliases	GTP-binding protein SAR1b, GTP-binding protein B, GTBPB, SAR1B, SARA2, SARB
Entrez GeneID	51128
Swissprot	Q9Y6B6
WB Predicted band size	22.4kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This SAR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids from the Central region of human SAR1B.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500
FCM	1/10-1/50

	SAR1B Antibody (Center) (Cat. #P30764) western blot analysis in MCF-7,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SAR1B antibody detected the SAR1B protein (arrow).
	SAR1B Antibody (Center) (Cat. #P30764) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
	SAR1B antibody (Center) (Cat. #P30764) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SAR1B antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.