中文 
别名:COVID-19; 2019-nCoV; SARS-CoV-2; spike glycoprotein; 新型冠状病毒; 新冠病毒应用:WB
反应种属:SARS-CoV-2/2019-nCoV、Virus
规格：50μl/100μl
| Description |
|---|
| Attaches the virion to the cell membrane by interacting with host receptor, initiating the infection (By similarity). Binding to human ACE2 receptor and internalization of the virus into the endosomes of the host cell induces conformational changes in the Spike glycoprotein (PubMed:32142651, PubMed:32075877, PubMed:32155444). Uses also human TMPRSS2 for priming in human lung cells which is an essential step for viral entry (PubMed:32142651). Proteolysis by cathepsin CTSL may unmask the fusion peptide of S2 and activate membranes fusion within endosomes. |
| Specification | |
|---|---|
| Aliases | COVID-19; 2019-nCoV; SARS-CoV-2; spike glycoprotein; 新型冠状病毒; 新冠病毒 |
| Swissprot | P0DTC2 |
| WB Predicted band size | 24 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | SARS-CoV-2/2019-nCoV、Virus |
| Immunogen | Fusion protein corresponding to a region derived from 805-1020 amino acids of SARS-CoV-2 S protein |
| Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Application | |
|---|---|
| WB | 1/5000-1/20000 |
| ELISA | 1/5000-1/10000 |
 |
Gel: 12%SDS-PAGE, Lysate: 1.25ug, 0.6ug, 0.3ug, Lane 1-3: 1.25ug, 0.6ug, 0.3ug Fusion protein of SARS-CoV-2 S2, Primary antibody: P02729(SARS-CoV-2 S2 Antibody) at dilution 1/5000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 second |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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