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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to SELENOF

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别名:SEP15
应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl

Description
The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. It has also been suggested to have a role in cancer etiology. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3′ UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene.
Specification
Aliases SEP15
Swissprot O60613
WB Predicted band size 18 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen Fusion protein of human SELENOF
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Application
WB 1/1000-1/5000
ELISA 1/5000-1/10000

Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Rat liver tissue lysate, Primary antibody: P02164(SELENOF Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 1 minute

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。