中文 
别名:Semaphorin-4A, Semaphorin-B, Sema B, SEMA4A, SEMAB, SEMB应用:WB
反应种属:Human, Mouse
规格：50μl/100μl
| Description |
|---|
| This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
| Specification | |
|---|---|
| Aliases | Semaphorin-4A, Semaphorin-B, Sema B, SEMA4A, SEMAB, SEMB |
| Entrez GeneID | 64218 |
| Swissprot | Q9H3S1 |
| WB Predicted band size | 83.6kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This SEMA4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 151-180 amino acids from the N-terminal region of human SEMA4A. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
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All lanes : Anti-SEMA4A Antibody (N-term) at 1:500 dilution Lane 1: HL-60 whole cell lysate Lane 2: THP-1 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 84 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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SEMA4A Antibody (N-term) (Cat. #P33765) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the SEMA4A antibody detected the SEMA4A protein (arrow). |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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