中文 
别名:Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Smt3ip2, Sentrin/SUMO-specific protease SENP2, SENP2, KIAA1331应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl
| Description |
|---|
| SUMO is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1, SUMO2, and SUMO3 into the conjugatable mature forms and catalyze the deconjugation of these same SUMO proteins from their targeted substrates. SENP2 may also down-regulate CTNNB1 levels and thereby modulate the Wnt pathway. |
| Specification | |
|---|---|
| Aliases | Sentrin-specific protease 2, Axam2, SMT3-specific isopeptidase 2, Smt3ip2, Sentrin/SUMO-specific protease SENP2, SENP2, KIAA1331 |
| Entrez GeneID | 59343 |
| Swissprot | Q9HC62 |
| WB Predicted band size | 67.9kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This SENP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 502-533 amino acids from the C-terminal region of human SENP2. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Application | |
|---|---|
| WB | 1/1000 |
| IHC | 1/100-1/500 |
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The SENP2 C-term polyclonal antibody (Cat. #P30004) is used in Western blot to detect SENP2 in mouse heart tissue lysate. |
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Western blot analysis of anti-SENP2 Antibody (C-term)(Cat. #P30004) in HL60 cell line lysates (35ug/lane). SENP2(arrow) was detected using the purified Pab. |
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Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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