Rabbit Polyclonal Antibody to SEPT6

包装: 1G|100G|500G|1KG|100KG

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别名:Septin-6, SEPT6, KIAA0128, SEP2
应用:WB
反应种属:Human, Mouse
规格：50μl/100μl

Description
This gene is a member of the septin family of GTPases. Members of this family are required for cytokinesis. One version of pediatric acute myeloid leukemia is the result of a reciprocal translocation between chromosomes 11 and X, with the breakpoint associated with the genes encoding the mixed-lineage leukemia and septin 2 proteins. This gene encodes four transcript variants encoding three distinct isoforms. An additional transcript variant has been identified, but its biological validity has not been determined.

Description

This gene is a member of the septin family of GTPases.
Members of this family are required for cytokinesis. One version of
pediatric acute myeloid leukemia is the result of a reciprocal
translocation between chromosomes 11 and X, with the breakpoint
associated with the genes encoding the mixed-lineage leukemia and
septin 2 proteins. This gene encodes four transcript variants
encoding three distinct isoforms. An additional transcript variant
has been identified, but its biological validity has not been
determined.

Specification
Aliases	Septin-6, SEPT6, KIAA0128, SEP2
Entrez GeneID	23157
Swissprot	Q14141
WB Predicted band size	49.7kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	This SEPT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 400-426 amino acids from the C-terminal region of human SEPT6.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000

	SEPT6 Antibody (C-term) (Cat. #P32031) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the SEPT6 antibody detected the SEPT6 protein (arrow).
	SEPT6 Antibody (C-term) (Cat. #P32031) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the SEPT6 antibody detected the SEPT6 protein (arrow).