中文 
别名:Sestrin-3, SESN3, SEST3应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl
| Description |
|---|
| Sestrins form a small family of redox enzymes which regulate accumulation of Reactive Oxygen Species. They protect cells and their DNA against oxidative damage and regulate cell growth and viability. These genes are often deregulated in cancers and their inactivation accelerates the growth of model tumors in mice. |
| Specification | |
|---|---|
| Aliases | Sestrin-3, SESN3, SEST3 |
| Entrez GeneID | 143686 |
| Swissprot | P58005 |
| WB Predicted band size | 57.3kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human, Mouse |
| Immunogen | This Sestrin-3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 320-347 amino acids from the Central region of human Sestrin-3. |
| Formulation | Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Application | |
|---|---|
| WB | 1/1000-1/2000 |
| IHC | 1/100-1/500 |
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Anti-Sestrin-3 Antibody (Center Y335) at 1:2000 dilution + LNCaP whole cell lysate
Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 57 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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Anti-Sestrin-3 Antibody (Center Y335) at 1:2000 dilution + LNCaP whole cell lysate
Lysates/proteins at 20 µg per lane. Secondary Predicted band size : 57 kDa Blocking/Dilution buffer: 5% NFDM/TBST. |
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Sestrin-3 Antibody (Center Y335) (Cat. #P34641) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the Sestrin-3 antibody detected the Sestrin-3 protein (arrow). |
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Sestrin-3 Antibody (Center Y335) (Cat. #P34641)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Sestrin-3 Antibody (Center Y335) for immunohistochemistry. Clinical relevance has not been evaluated. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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