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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to SF3B2

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别名:Splicing factor 3B subunit 2, Pre-mRNA-splicing factor SF3b 145 kDa subunit, SF3b145, SF3b150, Spliceosome-associated protein 145, SAP 145, SF3B2, SAP145
应用:WB
反应种属:Human, Mouse, Rat
规格:50μl/100μl

Description
This gene encodes subunit 2 of the splicing factor 3b
protein complex. Splicing factor 3b, together with splicing factor
3a and a 12S RNA unit, forms the U2 small nuclear
ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a
complex binds pre-mRNA upstream of the intron’s branch site in a
sequence-independent manner and may anchor the U2 snRNP to the
pre-mRNA. Splicing factor 3b is also a component of the minor
U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream
of the branch site at the anchoring site. Subunit 2 also interacts
directly with subunit 4 of the splicing factor 3b complex. Subunit
2 is a highly hydrophilic protein with a proline-rich N-terminus
and a glutamate-rich stretch in the C-terminus. [provided by
RefSeq].
Specification
Aliases Splicing factor 3B subunit 2, Pre-mRNA-splicing factor SF3b 145 kDa subunit, SF3b145, SF3b150, Spliceosome-associated protein 145, SAP 145, SF3B2, SAP145
Entrez GeneID 10992
Swissprot Q13435
WB Predicted band size 100.2kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human, Mouse, Rat
Immunogen This SF3B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 539-568 amino acids from the Central region of human SF3B2.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

SF3B2 Antibody (Center) (Cat. #P31598) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the SF3B2 antibody detected the SF3B2 protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。