Rabbit Polyclonal Antibody to SFRS7 (N-term)

包装: 1G|100G|500G|1KG|100KG

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别名:Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7, SRSF7, SFRS7
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene is a member of the serine/arginine (SR)-rich family of pre-mRNA splicing factors, which constitute part of the spliceosome. Each of these factors contains an RNA recognition motif (RRM) for binding RNA and an RS domain for binding other proteins. The RS domain is rich in serine and arginine residues and facilitates interaction between different SR splicing factors. In addition to being critical for mRNA splicing, the SR proteins have also been shown to be involved in mRNA export from the nucleus and in translation. Two transcript variants encoding different isoforms have been found for this gene.

Description

The protein encoded by this gene is a member of the
serine/arginine (SR)-rich family of pre-mRNA splicing factors,
which constitute part of the spliceosome. Each of these factors
contains an RNA recognition motif (RRM) for binding RNA and an RS
domain for binding other proteins. The RS domain is rich in serine
and arginine residues and facilitates interaction between different
SR splicing factors. In addition to being critical for mRNA
splicing, the SR proteins have also been shown to be involved in
mRNA export from the nucleus and in translation. Two transcript
variants encoding different isoforms have been found for this gene.

Specification
Aliases	Serine/arginine-rich splicing factor 7, Splicing factor 9G8, Splicing factor, arginine/serine-rich 7, SRSF7, SFRS7
Entrez GeneID	6432
Swissprot	Q16629
WB Predicted band size	27.4kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This SFRS7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 69-98 amino acids from the N-terminal region of human SFRS7.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	SFRS7 Antibody (N-term) (Cat. #P31067) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the SFRS7 antibody detected the SFRS7 protein (arrow).
	SFRS7 Antibody (N-term) (Cat. #P31067)immunohistochemistry analysis in formalin fixed and paraffin embedded human hepatocarcinoma tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SFRS7 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.