Rabbit Polyclonal Antibody to SFTPC (N-term)

包装: 1G|100G|500G|1KG|100KG

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别名:Pulmonary surfactant-associated protein C, SP-C, Pulmonary surfactant-associated proteolipid SPL(Val), SP5, SFTPC, SFTP2
应用:WB
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.

Description

This gene encodes the pulmonary-associated surfactant
protein C (SPC), an extremely hydrophobic surfactant protein
essential for lung function and homeostasis after birth. Pulmonary
surfactant is a surface-active lipoprotein complex composed of 90%
lipids and 10% proteins which include plasma proteins and
apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted
by the alveolar cells of the lung and maintains the stability of
pulmonary tissue by reducing the surface tension of fluids that
coat the lung. Multiple mutations in this gene have been
identified, which cause pulmonary surfactant metabolism dysfunction
type 2, also called pulmonary alveolar proteinosis due to
surfactant protein C deficiency, and are associated with
interstitial lung disease in older infants, children, and adults.
Alternatively spliced transcript variants encoding different
protein isoforms have been identified.

Specification
Aliases	Pulmonary surfactant-associated protein C, SP-C, Pulmonary surfactant-associated proteolipid SPL(Val), SP5, SFTPC, SFTP2
Entrez GeneID	6440
Swissprot	P11686
WB Predicted band size	21.1kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	This SFTPC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SFTPC.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.