Rabbit Polyclonal Antibody to SIX5

包装: 1G|100G|500G|1KG|100KG

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别名:DM locus-associated homeodomain protein; DMAHP; homeobox protein SIX5;
应用:WB
反应种属:Human,Mouse
规格：50μl/100μl

Description
Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5′-GGTGTCAG-3′ motif present in the ARE regulatory element of ATP1A1. Binds a 5′-TCA[AG][AG]TTNC-3′ motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter By similarity. Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 By similarity.Boucher C.A., Hum. Mol. Genet. 4:1919-1925(1995).Grimwood J., Nature 428:529-535(2004).The MGC Project Team; Genome Res. 14:2121-2127(2004).

Description

Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5′-GGTGTCAG-3′ motif present in the ARE regulatory element of ATP1A1. Binds a 5′-TCA[AG][AG]TTNC-3′ motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter By similarity. Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3 By similarity.Boucher C.A., Hum. Mol. Genet. 4:1919-1925(1995).Grimwood J., Nature 428:529-535(2004).The MGC Project Team; Genome Res. 14:2121-2127(2004).

Specification
Aliases	DM locus-associated homeodomain protein; DMAHP; homeobox protein SIX5;
Entrez GeneID	147912;
Swissprot	Q8N196
WB Predicted band size	75kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human SIX5.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.