Rabbit Polyclonal Antibody to SLC22A1

包装: 1G|100G|500G|1KG|100KG

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别名:Solute carrier family 22 member 1, Organic cation transporter 1, hOCT1, SLC22A1, OCT1
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
Polyspecific organic cation transporters in the liver, kidney, intestine, and other organs are critical for elimination of many endogenous small organic cations as well as a wide array of drugs and environmental toxins. This gene is one of three similar cation transporter genes located in a cluster on chromosome 6. The encoded protein contains twelve putative transmembrane domains and is a plasma integral membrane protein. Two transcript variants encoding two different isoforms have been found for this gene, but only the longer variant encodes a functional transporter. [provided by RefSeq].

Description

Polyspecific organic cation transporters in the liver,
kidney, intestine, and other organs are critical for elimination of
many endogenous small organic cations as well as a wide array of
drugs and environmental toxins. This gene is one of three similar
cation transporter genes located in a cluster on chromosome 6. The
encoded protein contains twelve putative transmembrane domains and
is a plasma integral membrane protein. Two transcript variants
encoding two different isoforms have been found for this gene, but
only the longer variant encodes a functional transporter. [provided
by RefSeq].

Specification
Aliases	Solute carrier family 22 member 1, Organic cation transporter 1, hOCT1, SLC22A1, OCT1
Entrez GeneID	6580
Swissprot	O15245
WB Predicted band size	61.2kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This SLC22A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 511-539 amino acids from the C-terminal region of human SLC22A1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	SLC22A1 Antibody (C-term) (Cat. #P31371) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the SLC22A1 antibody detected the SLC22A1 protein (arrow).
	SLC22A1 Antibody (C-term) (Cat. #P31371)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SLC22A1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.