Rabbit Polyclonal Antibody to SLC41A2

包装: 1G|100G|500G|1KG|100KG

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别名:SLC41A1-L1
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
SLC41A2 (solute carrier family 41, member 2), also known as SLC41A1-L, is a 573 amino acid multi-pass membrane protein that belongs to the SLC41A transporter family that includes SLC41A1 and SLC41A3. Expressed in lymphocytes and localizing to the cell membrane, SLC41A2 contains twelve transmembrane domains, three myristoylation sequences, numerous possible phosphorylation sites and a putative N-glycosylation site. SLC41A2 is believed to function as a plasma-membrane magnesium transporter. Magnesium, a cofactor for ATP, plays a vital role in metabolic and biochemical processes. The transport of magnesium across membranes is essential for maintaining magnesium homeostasis and is fundamental to vertebrate metabolism.

Description

SLC41A2 (solute carrier family 41, member 2), also known as SLC41A1-L, is a 573 amino acid multi-pass membrane protein that belongs to the SLC41A transporter family that includes SLC41A1 and SLC41A3. Expressed in lymphocytes and localizing to the cell membrane, SLC41A2 contains twelve transmembrane domains, three myristoylation sequences, numerous possible phosphorylation sites and a putative N-glycosylation site. SLC41A2 is believed to function as a plasma-membrane magnesium transporter. Magnesium, a cofactor for ATP, plays a vital role in metabolic and biochemical processes. The transport of magnesium across membranes is essential for maintaining magnesium homeostasis and is fundamental to vertebrate metabolism.

Specification
Aliases	SLC41A1-L1
Swissprot	Q96JW4
WB Predicted band size	62 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human SLC41A2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/20-1/100
ELISA	1/5000-1/10000

	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Human lung cancer tissue, Human lung adenocarcinoma tissue, Human liver cancer tissue lysates, Primary antibody: P12194(SLC41A2 Antibody) at dilution 1/250, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 4 minutes
	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12194(SLC41A2 Antibody) at dilution 1/20. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human brain tissue using P12194(SLC41A2 Antibody) at dilution 1/20. (Original magnification: ×200)