中文 
别名:BTR1; CDPD; CHED2; NABC1; SLC4A11应用:WB
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| Transporter which plays an important role in sodium-mediated fluid transport in different organs. Prevents severe morphological changes of the cornea caused by increased sodium chloride concentrations in the stroma. In the inner ear, is involved in transport of potassium through the fibrocyte layer to the stria vascularis and is essential for the generation of the endocochlear potential but not for regulation of potassium concentrations in the endolymph. In the kidney, is essential for urinary concentration, mediates a sodium flux into the thin descending limb of Henle loop to allow countercurrent multiplication by osmotic equilibration By similarity. Involved in borate homeostasis. In the absence of borate, it functions as a Na+ and OH-(H+) channel. In the presence of borate functions as an electrogenic Na+ coupled borate cotransporter.Parker M.D., Biochem. Biophys. Res. Commun. 282:1103-1109(2001).Deloukas P., Nature 414:865-871(2001).Ota T., Nat. Genet. 36:40-45(2004). |
| Specification | |
|---|---|
| Aliases | BTR1; CDPD; CHED2; NABC1; SLC4A11 |
| Entrez GeneID | 83959; |
| Swissprot | Q8NBS3 |
| WB Predicted band size | 100kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Synthesized peptide derived from internal of human SLC4A11. |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/3000 |
 |
Western blot analysis of extracts from 3T3 cells, RAW264.7 cells and A549 cells, using SLC4A11 antibody P42607. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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