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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to SLC5A12

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别名:Sodium-coupled monocarboxylate transporter 2, Electroneutral sodium monocarboxylate cotransporter, Low-affinity sodium-lactate cotransporter, Solute carrier family 5 member 12, SLC5A12, SMCT2
应用:WB,IHC,FCM
反应种属:Human
规格:50μl/100μl

Description
Normal blood lactate is maintained at about 1.5 mM, and
little filtered lactate is excreted in urine. Reabsorption of
lactate is mediated by the low-affinity Na(+)-coupled lactate
transporter SLC5A12 in the initial part of the proximal tubule and
by the high-affinity Na(+)-coupled lactate transporter SLC5A8 (MIM
608044) in the distal proximal tubule (Gopal et al., 2007 [PubMed
17692818]).
Specification
Aliases Sodium-coupled monocarboxylate transporter 2, Electroneutral sodium monocarboxylate cotransporter, Low-affinity sodium-lactate cotransporter, Solute carrier family 5 member 12, SLC5A12, SMCT2
Entrez GeneID 159963
Swissprot Q1EHB4
WB Predicted band size 67.6kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This SLC5A12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 576-605 amino acids from the C-terminal region of human SLC5A12.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/2000
IHC 1/100-1/500
FCM 1/10-1/50

Anti-SLC5A12 Antibody (C-term) at 1:2000 dilution + Y79 whole cell lysate

Lysates/proteins at 20 µg per lane.

Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.

Predicted band size : 68 kDa

Blocking/Dilution buffer: 5% NFDM/TBST.

SLC5A12 Antibody (C-term) (Cat. #P33591) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
SLC5A12 antibody (C-term) (Cat. #P33591) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SLC5A12 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.

本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。