库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to SMAC

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别名:SMAC; DFNA64; DIABLO; SMAC3
应用:WB,IHC,ICC,FCM,IP
反应种属:Human,Mouse,Rat
规格:50μl/100μl

Description
Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases.
Specification
Aliases SMAC; DFNA64; DIABLO; SMAC3
Entrez GeneID 56616
Swissprot Q9NR28
WB Predicted band size Calculated MW: 27 kDa; Observed MW: 21 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen A synthesized peptide derived from human Smac/Diablo
Formulation Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
IP 1/20
WB 1/500-1/1000
IHC 1/50-1/100
ICC 1/50-1/200
FCM 1/50-1/100

Western blot analysis of Smac/Diablo in Jurkat lysates using SMAC antibody.
Immunohistochemistry analysis of paraffin-embedded Human kidney using Smac/Diablo antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。