别名:SMAC; DFNA64; DIABLO; SMAC3应用:WB,IHC,ICC,FCM,IP
反应种属:Human,Mouse,Rat
规格:50μl/100μl
| Description |
|---|
| Smac/Diablo is a 21 kDa mammalian mitochondrial protein that functions as a regulatory component during apoptosis. Upon mitochondrial stress, Smac/Diablo is released from mitochondria and competes with caspases for binding of IAPs (inhibitor of apoptosis proteins). The interaction of Smac/Diablo with IAPs relieves the inhibitory effect of the IAPs on caspases. |
| Specification | |
|---|---|
| Aliases | SMAC; DFNA64; DIABLO; SMAC3 |
| Entrez GeneID | 56616 |
| Swissprot | Q9NR28 |
| WB Predicted band size | Calculated MW: 27 kDa; Observed MW: 21 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | A synthesized peptide derived from human Smac/Diablo |
| Formulation | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| IP | 1/20 |
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| ICC | 1/50-1/200 |
| FCM | 1/50-1/100 |
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Western blot analysis of Smac/Diablo in Jurkat lysates using SMAC antibody. |
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Immunohistochemistry analysis of paraffin-embedded Human kidney using Smac/Diablo antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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