中文 
别名:JV15-2; MAD-3; MADH3; Smad 3; Mothers against decapentaplegic homolog 3应用:WB
反应种属:Human,Mouse,Rat
规格：50μl/100μl
| Description |
|---|
| Smad3 encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene ‘mothers against decapentaplegic’ (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. Cohen-Solal KA, et al. (2011) Pigment Cell Melanoma Res 24, 512-24 Zelivianski S, Cooley A, Kall R, Jeruss JS (2010) Mol Cancer Res 8, 1375-87 Matsuura I, et al. (2010) J Biol Chem 285, 1754-64 |
| Specification | |
|---|---|
| Aliases | JV15-2; MAD-3; MADH3; Smad 3; Mothers against decapentaplegic homolog 3 |
| Entrez GeneID | 4088; |
| Swissprot | P84022 |
| WB Predicted band size | 50kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | Peptide sequence around phosphorylation site of threonine179(P-E-T(p)-P-P) derived from Human Smad3 . |
| Formulation | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
 |
Western blot analysis of extracts from HeLa cells treated with TNF using Phospho-Smad3 (Thr179) antibody P40591.The lane on the right is treated with the antigen-specific peptide. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
暂无评论
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
发表回复