Rabbit Polyclonal Antibody to SMARCE1

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1, BRG1-associated factor 57, BAF57, SMARCE1, BAF57
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
The protein encoded by this gene is part of the large ATP-dependent chromatin remodeling complex SWI/SNF, which is required for transcriptional activation of genes normally repressed by chromatin. The encoded protein, either alone or when in the SWI/SNF complex, can bind to 4-way junction DNA, which is thought to mimic the topology of DNA as it enters or exits the nucleosome. The protein contains a DNA-binding HMG domain, but disruption of this domain does not abolish the DNA-binding or nucleosome-displacement activities of the SWI/SNF complex. Unlike most of the SWI/SNF complex proteins, this protein has no yeast counterpart.

Description

The protein encoded by this gene is part of the large
ATP-dependent chromatin remodeling complex SWI/SNF, which is
required for transcriptional activation of genes normally repressed
by chromatin. The encoded protein, either alone or when in the
SWI/SNF complex, can bind to 4-way junction DNA, which is thought
to mimic the topology of DNA as it enters or exits the nucleosome.
The protein contains a DNA-binding HMG domain, but disruption of
this domain does not abolish the DNA-binding or
nucleosome-displacement activities of the SWI/SNF complex. Unlike
most of the SWI/SNF complex proteins, this protein has no yeast
counterpart.

Specification
Aliases	SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1, BRG1-associated factor 57, BAF57, SMARCE1, BAF57
Entrez GeneID	6605
Swissprot	Q969G3
WB Predicted band size	46.6kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This SMARCE1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-335 amino acids from the C-terminal region of human SMARCE1.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
IHC	1/100-1/500

	Western blot analysis of lysate from SK-BR-3 cell line, using SMARCE1 Antibody (C-term)(Cat. #P31454). P31454 was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
	SMARCE1 Antibody (C-term) (P31454)immunohistochemistry analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of SMARCE1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.