Rabbit Polyclonal Antibody to SNX13

包装: 1G|100G|500G|1KG|100KG

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别名:Sorting nexin-13, RGS domain- and PHOX domain-containing protein, RGS-PX1, SNX13, KIAA0713
应用:WB
反应种属:Human
规格：50μl/100μl

Description
This gene encodes a PHOX domain- and RGS domain-containing protein that belongs to the sorting nexin (SNX) family and the regulator of G protein signaling (RGS) family. The PHOX domain is a phosphoinositide binding domain, and the SNX family members are involved in intracellular trafficking. The RGS family members are regulatory molecules that act as GTPase activating proteins for G alpha subunits of heterotrimeric G proteins. The RGS domain of this protein interacts with G alpha(s), accelerates its GTP hydrolysis, and attenuates G alpha(s)-mediated signaling. Overexpression of this protein delayes lysosomal degradation of the epidermal growth factor receptor. Because of its bifunctional role, this protein may link heterotrimeric G protein signaling and vesicular trafficking.

Description

This gene encodes a PHOX domain- and RGS domain-containing
protein that belongs to the sorting nexin (SNX) family and the
regulator of G protein signaling (RGS) family. The PHOX domain is a
phosphoinositide binding domain, and the SNX family members are
involved in intracellular trafficking. The RGS family members are
regulatory molecules that act as GTPase activating proteins for G
alpha subunits of heterotrimeric G proteins. The RGS domain of this
protein interacts with G alpha(s), accelerates its GTP hydrolysis,
and attenuates G alpha(s)-mediated signaling. Overexpression of
this protein delayes lysosomal degradation of the epidermal growth
factor receptor. Because of its bifunctional role, this protein may
link heterotrimeric G protein signaling and vesicular trafficking.

Specification
Aliases	Sorting nexin-13, RGS domain- and PHOX domain-containing protein, RGS-PX1, SNX13, KIAA0713
Entrez GeneID	23161
Swissprot	Q9Y5W8
WB Predicted band size	112.2kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This SNX13 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-807 amino acids from the C-terminal region of human SNX13.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.