Rabbit Polyclonal Antibody to SOD2

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别名:IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD; SOD2
应用:WB
反应种属:Human,Mouse,Rat,Monkey
规格：50μl/100μl

Description
SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer’s disease, Parkinson’s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle.

Description

SOD-2 is a homotetrameric manganese enzyme (also known as MnSOD) that functions in the mitochondrion. ROS are implicated in a wide range of degenerative processes, including Alzheimer’s disease, Parkinson’s disease and ischemic heart disease. Homozygous mutant mice, which lack SOD-2, exhibit dilated cardiomyopathy, accumulation of lipid in liver and skeletal muscle, metabolic acidosis, oxidative DNA damage and respiratory chain deficiencies in heart and skeletal muscle.

Specification
Aliases	IPOB; IPO-B; MNSOD; MVCD6; Mn-SOD; SOD2
Entrez GeneID	6648
Swissprot	P04179
WB Predicted band size	Calculated MW: 25 kDa; Observed MW: 25 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat,Monkey
Immunogen	Synthetic peptide.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.

Application
WB	1/500-1/1000

	Western blot analysis of SOD2 in 293, COS7, C6, 3T3 and Hela lysates using SOD2 antibody.
	Western blot analysis of SOD2 in HepG2 and Raw264.7 lysates using SOD2 antibody.
	Western blot analysis of SOD2 in K562, 293T, 3T3 and Jurkat lysates using SOD2 antibody.