Rabbit Polyclonal Antibody to SP110

包装: 1G|100G|500G|1KG|100KG

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别名:IPR1; VODI; IFI41; IFI75
应用:WB,IHC
反应种属:Human
规格：50μl/100μl

Description
The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.

Description

The nuclear body is a multiprotein complex that may have a role in the regulation of gene transcription. This gene is a member of the SP100/SP140 family of nuclear body proteins and encodes a leukocyte-specific nuclear body component. The protein can function as an activator of gene transcription and may serve as a nuclear hormone receptor coactivator. In addition, it has been suggested that the protein may play a role in ribosome biogenesis and in the induction of myeloid cell differentiation. Alternative splicing has been observed for this gene and three transcript variants, encoding distinct isoforms, have been identified.

Specification
Aliases	IPR1; VODI; IFI41; IFI75
Swissprot	Q9HB58
WB Predicted band size	78 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Fusion protein of human SP110
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/50-1/200
ELISA	1/5000-1/10000

	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: LOVO cell lysate, Primary antibody: P03556(SP110 Antibody) at dilution 1/600, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 30 seconds
	The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P03556(SP110 Antibody) at dilution 1/85. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P03556(SP110 Antibody) at dilution 1/85. (Original magnification: ×200)