中文 
别名:SK 2; SK-2; SPK 2; SPK-2应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl
| Description |
|---|
| This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
| Specification | |
|---|---|
| Aliases | SK 2; SK-2; SPK 2; SPK-2 |
| Entrez GeneID | 56848; |
| Swissprot | Q9NRA0 |
| WB Predicted band size | 69kDa |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse |
| Immunogen | Fusion protein corresponding to residues near the C terminal of human sphingosine kinase 2 |
| Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
| Application | |
|---|---|
| WB | 1/200-1/1000 |
| IHC | 1/25-1/100 |
 |
Gel: 8%SDS-PAGE Lysates (from left to right): Mouse brain and liver tissue Amount of lysate: 40ug per lane Primary antibody: 1/200 dilution Secondary antibody dilution: 1/8000 Exposure time: 5 minutes |
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Immunohistochemical analysis of paraffin-embedded Human thyroid cancer tissue using P42808 at dilution 1/60. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的，不可用于人类或动物的临床诊断或治疗，非药用，非食用。
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