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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to SphK2 (phospho Thr614)

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别名:SPHK2; Sphingosine kinase 2; SK 2; SPK 2
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格:50μl/100μl

Description
sphingosine kinase 2(SPHK2) Homo sapiens This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011],
Specification
Aliases SPHK2; Sphingosine kinase 2; SK 2; SPK 2
Entrez GeneID 56848
Swissprot Q9NRA0
WB Predicted band size 69kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen The antiserum was produced against synthesized peptide derived from human SPHK2 around the phosphorylation site of Thr614. AA range:580-629
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Application
WB 1/500-1/2000
IHC 1/100 – 1/300
ELISA 1/5000


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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。