Rabbit Polyclonal Antibody to SphK2 (phospho Thr614)

包装: 1G|100G|500G|1KG|100KG

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别名:SPHK2; Sphingosine kinase 2; SK 2; SPK 2
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
sphingosine kinase 2(SPHK2) Homo sapiens This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011],

Description

sphingosine kinase 2(SPHK2) Homo sapiens This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Aug 2011],

Specification
Aliases	SPHK2; Sphingosine kinase 2; SK 2; SPK 2
Entrez GeneID	56848
Swissprot	Q9NRA0
WB Predicted band size	69kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	The antiserum was produced against synthesized peptide derived from human SPHK2 around the phosphorylation site of Thr614. AA range:580-629
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.