Rabbit Polyclonal Antibody to SPR1

包装: 1G|100G|500G|1KG|100KG

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别名:Sphingosylphosphorylcholine receptor; Ovarian cancer G-protein coupled receptor 1; OGR-1; G-protein coupled receptor 68; GPR12A
应用:WB
反应种属:Human,Mouse
规格：50μl/100μl

Description
Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer By similarity.An S., FEBS Lett. 375:121-124(1995).Xu Y., Genomics 35:397-402(1996).King M.M., Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.

Description

Proton-sensing receptor involved in pH homeostasis. May represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. Mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer By similarity.An S., FEBS Lett. 375:121-124(1995).Xu Y., Genomics 35:397-402(1996).King M.M., Submitted (APR-2004) to the EMBL/GenBank/DDBJ databases.

Specification
Aliases	Sphingosylphosphorylcholine receptor; Ovarian cancer G-protein coupled receptor 1; OGR-1; G-protein coupled receptor 68; GPR12A
Entrez GeneID	8111;
Swissprot	Q15743
WB Predicted band size	41kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human SPR1.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.