别名:MCM1应用:WB,IHC
反应种属:Human
规格:50μl/100μl
Description |
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This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). |
Specification | |
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Aliases | MCM1 |
Entrez GeneID | 6722; |
Swissprot | P11831 |
WB Predicted band size | 52kDa |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Synthetic peptide corresponding to residues near the C terminal of human serum response factor (c-fos serum response element-binding transcription factor) |
Formulation | Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol. |
Application | |
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WB | 1/200-1/1000 |
IHC | 1/50-1/200 |
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Gel: 10%SDS-PAGE Lysates (from left to right): HT-29 and Jurkat cell Amount of lysate: 50ug per lane Primary antibody: 1/400 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute |
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Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using P42875 at dilution 1/30. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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