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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to SRF

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别名:MCM1
应用:WB,IHC
反应种属:Human
规格:50μl/100μl

Description
This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs).
Specification
Aliases MCM1
Entrez GeneID 6722;
Swissprot P11831
WB Predicted band size 52kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen Synthetic peptide corresponding to residues near the C terminal of human serum response factor (c-fos serum response element-binding transcription factor)
Formulation Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.
Application
WB 1/200-1/1000
IHC 1/50-1/200

Gel: 10%SDS-PAGE Lysates (from left to right): HT-29 and Jurkat cell Amount of lysate: 50ug per lane Primary antibody: 1/400 dilution Secondary antibody dilution: 1/8000 Exposure time: 1 minute
Immunohistochemical analysis of paraffin-embedded Human cervical cancer tissue using P42875 at dilution 1/30.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。