Rabbit Polyclonal Antibody to STAG3

包装: 1G|100G|500G|1KG|100KG

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别名:Cohesin subunit SA-3; Stromal antigen 3; Stromalin 3; SCC3 homolog 3; STAG3
应用:WB
反应种属:Human
规格：50μl/100μl

Description
Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I By similarity.Pezzi N., FASEB J. 14:581-592(2000).The German cDNA consortium; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.Prieto I., EMBO Rep. 3:543-550(2002).

Description

Meiosis specific component of cohesin complex. The cohesin complex is required for the cohesion of sister chromatids after DNA replication. The cohesin complex apparently forms a large proteinaceous ring within which sister chromatids can be trapped. At anaphase, the complex is cleaved and dissociates from chromatin, allowing sister chromatids to segregate. The meiosis-specific cohesin complex probably replaces mitosis specific cohesin complex when it dissociates from chromatin during prophase I By similarity.Pezzi N., FASEB J. 14:581-592(2000).The German cDNA consortium; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.Prieto I., EMBO Rep. 3:543-550(2002).

Specification
Aliases	Cohesin subunit SA-3; Stromal antigen 3; Stromalin 3; SCC3 homolog 3; STAG3
Entrez GeneID	10734;
Swissprot	Q9UJ98
WB Predicted band size	139kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	Synthesized peptide derived from C-terminal of human STAG3.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.