Rabbit Polyclonal Antibody to STARD6

包装: 1G|100G|500G|1KG|100KG

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别名:StAR-related lipid transfer protein 6, START domain-containing protein 6, StARD6, STARD6
应用:WB,FCM
反应种属:Human
规格：50μl/100μl

Description
Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM 184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake. Sterol transport is mediated by vesicles or by soluble protein carriers, such as steroidogenic acute regulatory protein (STAR; MIM 600617). STAR is homologous to a family of proteins containing a 200- to 210-amino acid STAR-related lipid transfer (START) domain, including STARD6 (Soccio et al., 2002 [PubMed 12011452]).

Description

Cholesterol homeostasis is regulated, at least in part, by
sterol regulatory element (SRE)-binding proteins (e.g., SREBP1; MIM
184756) and by liver X receptors (e.g., LXRA; MIM 602423). Upon
sterol depletion, LXRs are inactive and SREBPs are cleaved, after
which they bind promoter SREs and activate genes involved in
cholesterol biosynthesis and uptake. Sterol transport is mediated
by vesicles or by soluble protein carriers, such as steroidogenic
acute regulatory protein (STAR; MIM 600617). STAR is homologous to
a family of proteins containing a 200- to 210-amino acid
STAR-related lipid transfer (START) domain, including STARD6
(Soccio et al., 2002 [PubMed 12011452]).

Specification
Aliases	StAR-related lipid transfer protein 6, START domain-containing protein 6, StARD6, STARD6
Entrez GeneID	147323
Swissprot	P59095
WB Predicted band size	25.0kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human
Immunogen	This STARD6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 187-215 amino acids from the C-terminal region of human STARD6.
Formulation	Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Application
WB	1/1000
FCM	1/10-1/50

	STARD6 Antibody (C-term) (Cat. #P31004) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the STARD6 antibody detected the STARD6 protein (arrow).
	STARD6 Antibody (C-term) (Cat. #P31004) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.