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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to STAT5B (Ab-731)

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别名:Signal transducer and activator of transcription 5B;
应用:WB,IHC
反应种属:Human,Mouse
规格:50μl/100μl

Description
Carries out a dual function: signal transduction and activation of transcription. Mediates cellular responses to the cytokine KITLG/SCF and other growth factors. Binds to the GAS element and activates PRL-induced transcription.Zsuzsanna S. Nagy, J. Leukoc. Biol., Oct 2002; 72: 819.Stanislaw M. Stepkowski, Blood, Jan 2002; 99: 680 – 689.Salvador Aznar Benitah, Mol. Biol. Cell, Jan 2003; 14: 40.
Specification
Aliases Signal transducer and activator of transcription 5B;
Entrez GeneID 6777;
Swissprot P51692
WB Predicted band size 90kDa
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse
Immunogen Synthesized non-phosphopeptide derived from human STAT5B around the phosphorylation site of serine 731(A-P-S-P-A).
Formulation Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Application
WB 1/500-1/3000
IHC 1/50-1/100

Western blot analysis of extracts from RAW264.7 cells, treated with EGF (200ng/ml 30min), using STAT5B (Ab-731) antibody P41639.
Immunohistochemical analysis of paraffin-embedded human colon carcinoma tissue using STAT5B (Ab-731) antibody P41639.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。