Rabbit Polyclonal Antibody to STK17B

包装: 1G|100G|500G|1KG|100KG

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别名:DRAK2
应用:IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
The full-length STK17B cDNA clone encodes a deduced 372-amino acid protein with a molecular mass of 42.34 kD. The putative kinase domain is located at the N terminus and contains all 11 subdomains conserved among ser/thr kinases. STK17A and STK17B share 59.7% amino acid identity. Northern blot analysis revealed that STK17B was expressed in various tissues, such as heart, placenta, liver, and pancreas, as different-sized transcripts, presumably due to differences in the 3-prime untranslated region. Transient transfection of COS-7 cells showed that STK17B localized in nuclei. Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis.

Description

The full-length STK17B cDNA clone encodes a deduced 372-amino acid protein with a molecular mass of 42.34 kD. The putative kinase domain is located at the N terminus and contains all 11 subdomains conserved among ser/thr kinases. STK17A and STK17B share 59.7% amino acid identity. Northern blot analysis revealed that STK17B was expressed in various tissues, such as heart, placenta, liver, and pancreas, as different-sized transcripts, presumably due to differences in the 3-prime untranslated region. Transient transfection of COS-7 cells showed that STK17B localized in nuclei. Phosphorylates myosin light chains. Acts as a positive regulator of apoptosis.

Specification
Aliases	DRAK2
Swissprot	O94768
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human STK17B
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/50-1/200
ELISA	1/1000-1/5000

	The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P08024(STK17B Antibody) at dilution 1/40. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P08024(STK17B Antibody) at dilution 1/40. (Original magnification: ×200)