Rabbit Polyclonal Antibody to STK3/STK4

包装: 1G|100G|500G|1KG|100KG

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别名:KRS1; MST2/KRS2; MST1; YSK3; TIIAC
应用:WB,IHC
反应种属:Human, Mouse
规格：50μl/100μl

Description
Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cyto-solic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to Ste20 are divided into two groups, the PAK subfamily and the GCK subfamily. The mammalian Ste20-like kinases (MST kinases), also known as Krs proteins, are members of the GCK subfamily. Ksr-1 (MST-2) and Ksr-2 (MST-1) are both direct substrates of caspase-3 that accelerate caspase-3 activation.

Description

Sterile-20 (Ste20) is a serine/threonine kinase in Saccharomyces cerevisiae that is involved in relaying signals from G protein-coupled receptors to cyto-solic MAP kinase cascades. Mammalian protein kinases that display sequence similarity to Ste20 are divided into two groups, the PAK subfamily and the GCK subfamily. The mammalian Ste20-like kinases (MST kinases), also known as Krs proteins, are members of the GCK subfamily. Ksr-1 (MST-2) and Ksr-2 (MST-1) are both direct substrates of caspase-3 that accelerate caspase-3 activation.

Specification
Aliases	KRS1; MST2/KRS2; MST1; YSK3; TIIAC
Swissprot	Q13043
WB Predicted band size	56 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse
Immunogen	Synthetic peptide of human STK3/STK4
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/100-1/300
ELISA	1/2000-1/10000

	Gel: 6%SDS-PAGE, Lysate: 40 μg, Lane 1-5: PC3 cells, hela cells, human bladder carcinoma tissue, A172 cells, hepG2 cells, Primary antibody: P11626(STK3/STK4 Antibody) at dilution 1/1000, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 10 seconds
	The image is immunohistochemistry of paraffin-embedded Human Lymphoma tissue using P11626(STK3/STK4 Antibody) at dilution 1/70. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P11626(STK3/STK4 Antibody) at dilution 1/70. (Original magnification: ×200)