Rabbit Polyclonal Antibody to STOML2

包装: 1G|100G|500G|1KG|100KG

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别名:SLP-2; HSPC108
应用:WB,IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
Stomatin-like protein 2 (STOML2), SLP-2 or EPB72-like 2, is a 356 amino acid member of the mec-2 family of proteins. Expressed ubiquitously at low levels, STOML2 is highly expressed in heart, liver and pancreas. STOML2 is localized to the cytoplasm with some distribution on the membrane. STOML2 was first identified as an overexpressed protein in human endometrial adenocarcinoma. Changes in cell growth in samples with different levels of STOML2 indicate that STOML2 could play a role in endometrial tumorigenesis. STOML2 is also thought to play a role in regulating ion channel conductances or the organization of sphingolipid and cholesterol-rich lipid rafts.

Description

Stomatin-like protein 2 (STOML2), SLP-2 or EPB72-like 2, is a 356 amino acid member of the mec-2 family of proteins. Expressed ubiquitously at low levels, STOML2 is highly expressed in heart, liver and pancreas. STOML2 is localized to the cytoplasm with some distribution on the membrane. STOML2 was first identified as an overexpressed protein in human endometrial adenocarcinoma. Changes in cell growth in samples with different levels of STOML2 indicate that STOML2 could play a role in endometrial tumorigenesis. STOML2 is also thought to play a role in regulating ion channel conductances or the organization of sphingolipid and cholesterol-rich lipid rafts.

Specification
Aliases	SLP-2; HSPC108
Swissprot	Q9UJZ1
WB Predicted band size	39 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Fusion protein of human STOML2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
WB	1/500-1/2000
IHC	1/20-1/100
ELISA	1/5000-1/10000

	Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-3: Mouse brain tissue, Rat heart tissue, Rat brain tissue lysates, Primary antibody: P09676(STOML2 Antibody) at dilution 1/350, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 5 seconds
	The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P09676(STOML2 Antibody) at dilution 1/25. (Original magnification: ×200)