Rabbit Polyclonal Antibody to Superoxide Dismutase 1

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别名:SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions.

Description

SOD1, Cu/Zn superoxide dismutase, is a major antioxidant enzyme that catalyzes the conversion of superoxide anion to hydrogen peroxide and molecular oxygen. The mechanism by which mutant SOD1 induces the neurodegeneration observed in ALS is still unclear. Mutant SOD1 proteins become misfolded and consequently oligomerize into high molecular weight species that aggregate and end up in proteinaceous inclusions.

Specification
Aliases	SOD1; Superoxide dismutase [Cu-Zn]; Superoxide dismutase 1; hSod1
Entrez GeneID	6647
Swissprot	P00441
WB Predicted band size	Calculated MW: 16 kDa; Observed MW: 16 kDa
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Synthesized peptide derived from the Internal region of human SOD-1.
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.