Rabbit Polyclonal Antibody to Synaptotagmin (Phospho-Thr202)

包装: 1G|100G|500G|1KG|100KG

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别名:LAG; LAP18; STN1; Prosolin; stathmin
应用:WB,IHC
反应种属:Human,Mouse,Rat
规格：50μl/100μl

Description
The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse. E Carafoli, Crit. Rev. Biochem. Mol. Biol., Apr 2001; 36: 107. Gry Houeland, J Neurophysiol, Jan 2007; 97: 134 – 143Christelle Carteron, J. Cell Sci., Mar 2006; 119: 898 – 909Vladimir I. Slepnev, Science, Aug 1998; 281: 821

Description

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Calcium binding to synaptotagmin I participates in triggering neurotransmitter release at the synapse. E Carafoli, Crit. Rev. Biochem. Mol. Biol., Apr 2001; 36: 107. Gry Houeland, J Neurophysiol, Jan 2007; 97: 134 – 143Christelle Carteron, J. Cell Sci., Mar 2006; 119: 898 – 909Vladimir I. Slepnev, Science, Aug 1998; 281: 821

Specification
Aliases	LAG; LAP18; STN1; Prosolin; stathmin
Entrez GeneID	6857;
Swissprot	P21579
WB Predicted band size	60kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse,Rat
Immunogen	Peptide sequence around phosphorylation site of threonine 202(R-K-T(p)-L-N) derived from Human Synaptotagmin.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/1000
IHC	1/50-1/100

	Western blot analysis of extracts from colo cells (Lane 2), using Synaptotagmin (Phospho-Thr202) Antibody P40367. The lane on the left is treated with antigen-specific peptide.
	Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using Synaptotagmin (phospho-Thr202) antibody P40367 (left)or the same antibody preincubated with blocking peptide (right).