Rabbit Polyclonal Antibody to TADA2A

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别名:ADA2; ADA2A; KL04P; hADA2; TADA2L
应用:IHC
反应种属:Human, Mouse, Rat
规格：50μl/100μl

Description
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined.

Description

Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined.

Specification
Aliases	ADA2; ADA2A; KL04P; hADA2; TADA2L
Swissprot	O75478
Host/Isotype	Rabbit IgG
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human, Mouse, Rat
Immunogen	Synthetic peptide of human TADA2A
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Application
IHC	1/25-1/100
ELISA	1/2000-1/5000

	The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using P11422(TADA2A Antibody) at dilution 1/25. (Original magnification: ×200)
	The image is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using P11422(TADA2A Antibody) at dilution 1/25. (Original magnification: ×200)