Rabbit Polyclonal Antibody to TAF1

包装: 1G|100G|500G|1KG|100KG

现货支持定制

QQ咨询
| 微信咨询

400-880-2824

满200元免运费
正品保障提供发票
现货闪电当时发货

别名:BA2R; CCG1; Cell cycle gene 1 protein; EC 2.7.11.1; P250
应用:IHC
反应种属:Human,Mouse
规格：50μl/100μl

Description
Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on ‘Thr-55’ which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Exhibits histone acetyltransferase activity towards histones H3 and H4.Sekiguchi T., Mol. Cell. Biol. 11:3317-3325(1991).Ruppert S., Nature 362:175-179(1993).Nolte D., Proc. Natl. Acad. Sci. U.S.A. 100:10347-10352(2003).

Description

Largest component and core scaffold of the TFIID basal transcription factor complex. Contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. Phosphorylates TP53 on ‘Thr-55’ which leads to MDM2-mediated degradation of TP53. Phosphorylates GTF2A1 and GTF2F1 on Ser residues. Possesses DNA-binding activity. Essential for progression of the G1 phase of the cell cycle. Exhibits histone acetyltransferase activity towards histones H3 and H4.Sekiguchi T., Mol. Cell. Biol. 11:3317-3325(1991).Ruppert S., Nature 362:175-179(1993).Nolte D., Proc. Natl. Acad. Sci. U.S.A. 100:10347-10352(2003).

Specification
Aliases	BA2R; CCG1; Cell cycle gene 1 protein; EC 2.7.11.1; P250
Entrez GeneID	6872;
Swissprot	P21675
WB Predicted band size	213kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human TAF1.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.