Rabbit Polyclonal Antibody to TAF5

包装: 1G|100G|500G|1KG|100KG

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别名:Transcription initiation factor TFIID subunit 5; Transcription initiation factor TFIID 100 kDa subunit; TAF(II)100; TAFII-100; TAFII100
应用:WB,IHC
反应种属:Human,Mouse
规格：50μl/100μl

Description
TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. TAF5/TAFII100 interacts strongly with the histone H4-related TAF6/TAFII80 and the histone H3-related TAF9/TAFII31, as well as a stable complex comprised of both TAF5/TAFII80 and TAF6/TAFII31. Apparently weaker interactions of TAF5/TAFII100 with TBP, TAF1/TAFII250, TAF11/TAFII28, and TAF12/TAFII20, but not TAF7/TAFII55, also have been observed.Dubrovskaya V., EMBO J. 15:3702-3712(1996).Tanese N., Proc. Natl. Acad. Sci. U.S.A. 93:13611-13616(1996).Tao Y., J. Biol. Chem. 272:6714-6721(1997).

Description

TAFs are components of the transcription factor IID (TFIID) complex, PCAF histone acetylase complex and TBP-free TAFII complex (TFTC). TAFs components-TIIFD are essential for mediating regulation of RNA polymerase transcription. TAF5/TAFII100 interacts strongly with the histone H4-related TAF6/TAFII80 and the histone H3-related TAF9/TAFII31, as well as a stable complex comprised of both TAF5/TAFII80 and TAF6/TAFII31. Apparently weaker interactions of TAF5/TAFII100 with TBP, TAF1/TAFII250, TAF11/TAFII28, and TAF12/TAFII20, but not TAF7/TAFII55, also have been observed.Dubrovskaya V., EMBO J. 15:3702-3712(1996).Tanese N., Proc. Natl. Acad. Sci. U.S.A. 93:13611-13616(1996).Tao Y., J. Biol. Chem. 272:6714-6721(1997).

Specification
Aliases	Transcription initiation factor TFIID subunit 5; Transcription initiation factor TFIID 100 kDa subunit; TAF(II)100; TAFII-100; TAFII100
Entrez GeneID	6877;
Swissprot	Q15542
WB Predicted band size	87kDa
Storage	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity	Human,Mouse
Immunogen	Synthesized peptide derived from internal of human TAF5.
Formulation	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Application
WB	1/500-1/3000
IHC	1/50-1/100

	Western blot analysis of extracts from A549 cells, using TAF5 antibody P42006.
	Immunohistochemistry analysis of paraffin-embedded human liver carcinoma tissue using TAF5 antibody P42006.