别名:MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1应用:WB,IHC,ICC
反应种属:Human,Mouse,Rat
规格:50μl/100μl
| Description |
|---|
| Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B. |
| Specification | |
|---|---|
| Aliases | MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1 |
| Entrez GeneID | 6885 |
| Swissprot | O43318 |
| WB Predicted band size | Calculated MW: 67 kDa; Observed MW: 70 kDa |
| Host/Isotype | Rabbit IgG |
| Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
| Species Reactivity | Human,Mouse,Rat |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MAP3K7. AA range:161-210 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3. |
| Application | |
|---|---|
| WB | 1/500-1/1000 |
| IHC | 1/50-1/100 |
| ICC | 1/50-1/200 |
| ELISA | 1/10000 |
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Western blot analysis of TAK1 in Jurkat lysates, treated with heat shock lysates using TAK1 antibody. The lane on the right is blocked with the synthesized peptide. |
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Immunofluorescence analysis of TAK1 in rat kidney using Tak1 antibody(red),and DAPI (blue). |
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Immunofluorescence analysis of TAK1 in mouse kidney using Tak1 antibody(red),and DAPI (blue). |
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Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma using TAK1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right. |
本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。
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