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瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to TAK1

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别名:MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1
应用:WB,IHC,ICC
反应种属:Human,Mouse,Rat
规格:50μl/100μl

Description
Component of a protein kinase signal transduction cascade. Mediator of TRAF6 and TGF-beta signal transduction. Activates IKBKB and MAPK8 in response to TRAF6 signaling. Stimulates NF-kappa-B activation and the p38 MAPK pathway. In osmotic stress signaling, plays a major role in the activation of MAPK8/JNK, but not that of NF-kappa-B.
Specification
Aliases MAP3K7; TAK1; Mitogen-activated protein kinase kinase kinase 7; Transforming growth factor-beta-activated kinase 1; TGF-beta-activated kinase 1
Entrez GeneID 6885
Swissprot O43318
WB Predicted band size Calculated MW: 67 kDa; Observed MW: 70 kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human,Mouse,Rat
Immunogen The antiserum was produced against synthesized peptide derived from human MAP3K7. AA range:161-210
Formulation Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Application
WB 1/500-1/1000
IHC 1/50-1/100
ICC 1/50-1/200
ELISA 1/10000

Western blot analysis of TAK1 in Jurkat lysates, treated with heat shock lysates using TAK1 antibody. The lane on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of TAK1 in rat kidney using Tak1 antibody(red),and DAPI (blue).
Immunofluorescence analysis of TAK1 in mouse kidney using Tak1 antibody(red),and DAPI (blue).
Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma using TAK1 antibody.High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval. Sample with blocking peptide on the right.

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。