库存-现货
瑞威尔生物科技 REVERE

Rabbit Polyclonal Antibody to TAPBP (N-term)

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别名:Tapasin, TPN, TPSN, NGS-17, TAP-associated protein, TAP-binding protein, TAPBP, NGS17, TAPA
应用:WB
反应种属:Human
规格:50μl/100μl

Description
This gene encodes a transmembrane glycoprotein which
mediates interaction between newly assembled major
histocompatibility complex (MHC) class I molecules and the
transporter associated with antigen processing (TAP), which is
required for the transport of antigenic peptides across the
endoplasmic reticulum membrane. This interaction is essential for
optimal peptide loading on the MHC class I molecule. Up to four
complexes of MHC class I and this protein may be bound to a single
TAP molecule. This protein contains a C-terminal double-lysine
motif (KKKAE) known to maintain membrane proteins in the
endoplasmic reticulum. This gene lies within the major
histocompatibility complex on chromosome 6. Alternative splicing
results in three transcript variants encoding different isoforms.
Specification
Aliases Tapasin, TPN, TPSN, NGS-17, TAP-associated protein, TAP-binding protein, TAPBP, NGS17, TAPA
Entrez GeneID 6892
Swissprot O15533
WB Predicted band size 47.6kDa
Host/Isotype Rabbit IgG
Storage Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species Reactivity Human
Immunogen This TAPBP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-70 amino acids from the N-terminal region of human TAPBP.
Formulation Purified polyclonal antibody supplied in PBS with 0.05% sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Application
WB 1/1000

TAPBP Antibody (N-term) (Cat. #P32035) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the TAPBP antibody detected the TAPBP protein (arrow).

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本公司的所有产品仅用于科学研究或者工业应用等非医疗目的,不可用于人类或动物的临床诊断或治疗,非药用,非食用。